LifeASSURE™ PDA Series

Sterilizing Grade Polyethersulfone Membrane Filters

3M Purification Inc.'s LifeASSURETM PDA series filter combines two asymmetric polyethersulfone (PES) membrane layers together with Advanced Pleat Technology (APT) design. This design results in a robust filter that is optimized for both high throughput and fast flow applications while offering 0.2 μm absolute rated filtration for sterilizing performance. The unique hydrophilic polyethersulfone membrane wets easily for integrity testing and is ideal for applications where low protein binding is critical.


5 to 40”

Materials of Constructions

Cage, Core, End Caps, Adapters Polypropylene
Membrane Polyethersulfone
Membrane Support Layer Polypropylene
Encapsulated Adapter Reinforcing Ring Polysulfone

Filter Rating

0.2 μm

Filtration Surface Area

m2 (ft2)
5”: 0.35 (3.8) 10”: 0.78 (8.4)*

Typical Water Flow Rate

At 25 ̊C (77 ̊F): 5”: 8.8 (1.6)
lpm/100 mbar (gpm/psid) 10”: 19.8 (3.6)
20”: 35.7 (6.5)
30”: 49.4 (9.0)
40”: 49.4 (9.0)

Maximum Operation Temperature

80 ̊C (176 ̊F)

Maximum Differential Pressure

Forward Pressure: 5.5 (80) @ 25 ̊C (77 ̊F); 1.7 (25) @ 80 ̊C (176 ̊F) bar (psid)

Reverse Pressure: 2.4 (35) @ 25 ̊C (77 ̊F) bar (psid)

In-situ Steam Conditions

Up to 135 ̊C (275 ̊F)

Autoclave Conditions

Up to 126 ̊C (258.8 ̊F)


LifeASSURE™ PSA series filters are optimized for applications requiring critical sterilization where 0.2 μm absolute rated filtration is required.

  • Final 0.2 μm sterilizing filtration
  • Media and fermenter feed streams
  • Serum and blood fractions
  • Biologicals
  • Vaccines
  • Chromatography column protection
  • Cell culture fluids
  • High protein feed streams
  • Parenterals (SVP, LVP)
  • Reagents and Buffers
  • Solvent filtration Reagents & Buffers
  • Ophthalmics
  • High purity DI water and WFI systems
  • Bulk pharmaceutical chemicals
  • Orals and Topicals


  • Robust double membrane layer filter construction
  • Hydrophilic asymmetric polyethersulfone membrane
  • Validated 0.2 μm absolute-rated membrane
  • Advanced Pleat Technology construction
  • 100% Integrity tested prior to release
  • 21 CFR compliant materials of construction, USP Biological Reactivity Test for Plastics Class VI, Validation Guide and Drug Master File (DMF)


  • Exceptionally high contaminant capacity and fast flow rates for long on- stream life and maximum economy
  • Ensures easy wet out for integrity testing and low protein binding
  • Reliable sterilizing filtration
  • Allows maximum fluid and contaminant access to filter surface area for highest throughput
  • Ensures consistent performance to specification
  • Eases validation and regulatory submissions
RR Retention Rating
MT Maximum temperature recommended of a working product in degrees centigrade
MoC Primary material of construction
MoC Primary material of construction
MP Maximum working pressure of housing in bar
Brand Manufacturing brand name supplying the product
FE Filter efficiency
Q Quality assurances and certificates validating this product