Fluorofil™ Plus

High Flow Sterile Gas Filter with ePTFE Membrane

Fluorofil™ Plus cartridges are manufactured using a highly hydrophobic ePTFE membrane. The enhanced ePTFE membrane offers exceptionally high gas flow rates at low pressure differentials (see graph). Fluorofil™ Plus cartridges are recommended for sterile gas filtration and venting applications. The hydrophobic characteristics of the ePTFE membrane makes the Fluorofil™ Plus filter cartridge particularly suitable for wet gas sterilising applications, such as fermenter air feed.

Features and Benefits

  • Guaranteed microbial ratings in a liquid challenge
    Fluorofil™ Plus cartridges are validated for bacterial removal according to HIMA guidelines and ASTM F838-05, with a log reduction value >7.
  • High Flow ΔP characteristics
    The unique characteristics of the ePTFE membrane, having higher surface area, combined with the construction of the Fluorofil™ Plus filter cartridge, results in exceptionally high gas flow rates at low pressure differentials. These features result in lower energy consumption and fewer filter cartridges per system.
  • Mechanical strength
    Fluorofil™ Plus cartridges incorporate a stainless steel central core which provides greater mechanical strength. This allows the filter to be used at higher gas flow rates with low pressure differentials.
  • Cartridge integrity and low TOC levels
    All Fluorofil™ Plus cartridges are integrity tested and supplied clean, having been flushed with pure water.

Materials of Manufacture

Filter membrane: ePTFE
Membrane support: Polypropylene
Irrigation mesh (support): Polypropylene
Drainage layer: Polypropylene
Inner core: 316L Stainless Steel
Outer support: Polypropylene
End fittings: Polypropylene
Sealing: Fusion bonding

Gaskets and O-Rings

Ethylene Propylene, PTFE encapsulated, Silicone or Nitrile.

Maximum Differential Pressure

Normal flow direction at:
20°C (68°F): 6.0 bar (87lb/in2)
80°C (176°F): 4.0bar (58lb/in2)
100°C (212°F): 3.0 bar (43lb/in2)
120°C (248°F): 2.0 bar (29lb/in2)
125°C (257°F): 1.5bar (22lb/in2)
Reverse flow direction at:
20°C (68°F): 2.1bar (30lb/in2)
80°C (176°F): 1.0bar (15lb/in2)
100°C (212°F): 0.5bar (7lb/in2)

Operating Temperature

Maximum continuous: 80°C (176°F).


In situ steam 100 x 20 minute cycles at 135°C (275°F) to 150 x 20 minute cycles at 125°C (257°F).

Effective Filtration Area

Absolute Microbial Rating Effective Filtration Area (each 254mm (10") module)
0.2μm 0.8m2 (8.6ft2)


  • Sterile process gases
    The supply of sterile gas for critical applications in the pharmaceutical, biotechnology, food and beverage markets.
  • Sterile vents
    The safe sterile venting of processing vessels in pharmaceutical, fermentation, and food and beverage processes.
  • Biotechnology
    The sterile filtration of exhaust gases from biological fermenters.
  • Powder handling and tabletting
    The removal of ultrafine powder particles from compounding environments.

Gas Flow Rates


RR Retention Rating
MT Maximum temperature recommended of a working product in degrees centigrade
MoC Primary material of construction
MoC Primary material of construction
MP Maximum working pressure of housing in bar
Brand Manufacturing brand name supplying the product
FE Filter efficiency
Q Quality assurances and certificates validating this product