Biofil™ II

Polyethersulphone Membrane Cartridge Filters

A range of microbially rated cartridge filters from Porvair Filtration Group, featuring the latest developments in membrane technology, Biofil™ II cartridges are based on a naturally hydrophilic polyethersulphone (PES) membrane with a mirrored asymmetric pore structure. When combined with quality all- polypropylene cartridge components and high integrity manufacturing techniques common to all Porvair cartridge filters, the polyethersulphone membrane provides a high strength, long life cartridge of consistently precise microbial retention.

Features and Benefits

  • Guaranteed microbial ratings
    Biofil™ II cartridges are validated for bacterial removal according to HIMA guidelines and ASTM F838-05, with a log reduction value >7. They are therefore suitable for applications requiring sterilising grade filtration.
  • Low protein binding
    Biofil™ II cartridges have excellent low protein binding characteristics, typically 10 times lower than nylon, 2 times lower than polysulphone and similar to PVDF.
  • Will not hydrolyse
  • Excellent chemical compatibility
  • Cartridge integrity and low TOC levels
    Each Biofil™ II module of every cartridge is individually integrity tested. Each complete filter cartridge is flushed with pure water which is inspected daily for pyrogens using the standard LAL test. When required, they can be pulse flushed with 18MΩ.cm pyrogen-free ultra-clean water.
  • Suitable for steam sterilising
  • Full traceability
  • Controlled manufacturing environment

Materials of Manufacture

Filter membrane: Polyethersulphone
Membrane support: Polypropylene
Irrigation mesh (support): Polypropylene
Drainage layer: Polypropylene
Inner core: Polypropylene
Outer support: Polypropylene
End fittings: Polypropylene
Support ring: Stainless steel

Gaskets and O-Rings

FDA approved Ethylene Propylene, PTFE encapsulated, Silicone or Nitrile.

Maximum Differential Pressure

Normal flow direction at:
20°C (68°F): 6.0 bar (87lb/in2)
80°C (176°F): 4.0 bar (58lb/in2)
100°C (212°F): 3.0 bar (43lb/in2)
120°C (248°F): 2.0 bar (29lb/in2)


In situ steam 80 x 20 minute cycles at 125°C (257°F).
Hot water 100 x 20 minute cycles at 85-90°C (185-194°F).

Effective Filtration Area

Pore Size Rating Effective Filtration Area (each 254mm (10") module)
0.04, 0.1, 0.2, 0.45, 0.65 and 1.2μm 0.69m2 (7.4ft2)

Operating Temperature

Maximum continuous: 60°C (140°F)


  • Biopharmaceuticals
    For the sub-micronic filtration of ingredients, intermediates, make-up waters and final products, including sterilisation, clarification and bioburden reduction.
  • Opthalmic solutions
    Shelf life assured through the non-removal of preservatives, such as Benzalkonium Chloride (BAK).
  • Electronics and semiconductors
    For the sub-micronic filtration of process water and chemicals, including solvents, developers and photoresists. Applications typically include central water plant treatment and critical 'wet bench' point of use filtration.
  • Fine chemicals
  • Beverages
  • Pure water supply

Clean Water Flow Rates


RR Retention Rating
MT Maximum temperature recommended of a working product in degrees centigrade
MoC Primary material of construction
MoC Primary material of construction
MP Maximum working pressure of housing in bar
Brand Manufacturing brand name supplying the product
FE Filter efficiency
Q Quality assurances and certificates validating this product